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In vitro drug conversation studies have demonstrated that mitoxantrone did not inhibit CYP450 1A2, 2A6, 2C9, 2C19, 2D6, 2E1 and 3A4 throughout a broad concentration range. The outcome of in vitro induction scientific studies are inconclusive, but suggest that mitoxantrone could be a weak inducer of CYP450 2E1 activity. Pharmacokinetic research of y